NIH-funded research R01 grant

Advanced 3D imaging technology for observing nanoscale biological structures

Official title: Three-Dimensional (3D) Acoustofluidic Scanning Nanoscope with Super Resolution and Large Field of View

Funded at University of Dayton · NIH-10886747 · Data updated 2026-11-12

This study is exploring a new 3D imaging tool that helps scientists see tiny biological structures more clearly, which could lead to better ways to diagnose and treat diseases that affect you.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Dayton
NIH-funded
Lab location1 site (Dayton, United States)
Project startSeptember 15, 2021
Project endJuly 31, 2025
Funding year2024
Award (this year)$370,593
NIH project number5R01GM143439-04
Project IDNIH-10886747 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals with conditions that involve cellular abnormalities or diseases where detailed cellular imaging could provide critical insights.

Less likely to help

Patients with conditions that do not involve cellular imaging or those who are not undergoing treatment that requires detailed biological analysis may not benefit from this research.

What this research studies

This research focuses on developing a new type of 3D imaging technology called an acoustofluidic scanning nanoscope, which allows scientists to visualize biological structures at the nanoscale with unprecedented detail. By combining super-resolution imaging with a large field of view, this technology aims to overcome the limitations of traditional imaging methods. Patients may benefit from insights gained into cellular processes that could lead to improved diagnostics and treatments for various diseases. The research involves validating the imaging capabilities through rigorous testing and comparison with existing techniques.

Why it matters

Potential benefit: If successful, this research could lead to breakthroughs in understanding cellular functions and disease mechanisms, ultimately improving patient care.

How similar studies have gone: Previous advancements in super-resolution imaging technologies have shown significant success, indicating a strong potential for this novel approach.

Where this research is happening

  • University of Dayton
    Dayton, United States
    Active

Researchers

  • Principal investigator: Agha, Imad — University of Dayton
  • Study coordinator: Agha, Imad

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.