Administrative hub for projects on how the heart's ventricles form
Administrative Core
This program coordinates teams working to understand why the heart's ventricles form abnormally in babies with congenital heart disease.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project ID | NIH-11299541 on NIH RePORTER |
What this research studies
As a parent, I would see this program as the administrative hub that brings several labs together to study how ventricles develop in the unborn baby. It helps share resources, standardize methods, and make sure experiments meet safety and ethical rules. The actual lab projects use animal models and molecular and genetic tools to trace the cells and pathways that shape the ventricle. The core's coordination aims to speed discoveries by improving collaboration and data sharing across the program.
Who could benefit from this research
Good fit: The most relevant patients would be infants and families affected by congenital heart defects that alter ventricular shape or function, though this administrative core itself does not directly enroll patients.
Not a fit: Adults with acquired heart disease or patients with congenital problems that do not involve the ventricles are less likely to directly benefit from this specific program.
Why it matters
Potential benefit: If successful, this work could lead to better diagnosis, prevention, or treatments for babies born with ventricular congenital heart defects.
How similar studies have performed: Previous developmental and animal-model research has uncovered some heart formation pathways, but many causes of ventricular congenital heart defects remain unknown, so this program builds on earlier work while exploring new mechanisms.
Where this research is happening
Indianapolis, United States
- Indiana University Indianapolis — Indianapolis, United States (Active)
Researchers
- Principal investigator: Firulli, Anthony B. — Indiana University Indianapolis
- Study coordinator: Firulli, Anthony B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.