Administrative center supporting Alzheimer's disease and Lewy body disorder projects
Core A: Administrative Core
This center helps teams use human brain and fluid samples to learn why some people with Lewy body disorders or Alzheimer's develop dementia while others do not.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11184444 on NIH RePORTER |
What this research studies
We coordinate and support a Penn program focused on Alzheimer's disease and Lewy body disorders. The Administrative Core runs meetings, manages budgets, and connects the different projects so they can share samples, data, and ideas. The work centers on human-derived brain tissue and biofluids already collected from people with neurodegenerative conditions to look for biological differences linked to dementia. An external advisory committee that includes someone affected by a Lewy body disorder helps guide the center toward work that matters to patients.
Who could benefit from this research
Good fit: Ideal candidates include people with Lewy body disorders, Alzheimer's disease, or related dementias and individuals willing to donate blood, cerebrospinal fluid, or brain tissue for research.
Not a fit: People without dementia-related conditions or those not willing to provide samples or participate in research are unlikely to directly benefit from this center's activities.
Why it matters
Potential benefit: If successful, this work could point to biological targets that lead to new treatments to prevent or slow dementia in people with Lewy body disorders and related Alzheimer's disease.
How similar studies have performed: Previous studies using human brain tissue and biofluids have identified important disease clues, but turning those findings into effective treatments has remained difficult.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Chen-Plotkin, Alice S — University of Pennsylvania
- Study coordinator: Chen-Plotkin, Alice S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.