Addressing mental health and social issues in people with HIV in South Africa

Developing and piloting a multilevel intervention to address psychosocial and structural syndemics in people with HIV in South Africa

NIH-funded research Massachusetts General Hospital · NIH-11035099

This study is looking to help people living with HIV in South Africa by addressing both mental health challenges, like depression and stress, and practical issues, like not having enough food, to make it easier for them to stick to their treatment and feel healthier overall.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11035099 on NIH RePORTER

What this research studies

This research aims to develop and test a comprehensive intervention that tackles both psychosocial issues, like depression and post-traumatic stress, and structural challenges, such as food insecurity, that affect people living with HIV in South Africa. By focusing on these interconnected problems, the study seeks to improve adherence to antiretroviral therapy (ART) and overall health outcomes. The approach includes training and mentorship for the principal investigator to ensure effective implementation and evaluation of the intervention in a resource-limited setting.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living with HIV in South Africa who are experiencing psychosocial challenges or structural issues that impact their health.

Not a fit: Patients who are not living with HIV or those who do not face psychosocial or structural challenges may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly enhance the quality of life and health outcomes for individuals living with HIV by improving their adherence to treatment.

How similar studies have performed: Previous research has shown that addressing psychosocial and structural factors can improve health outcomes for individuals with HIV, indicating a promising approach.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.