NIH-funded research R01 grant

Adding yoga to a weight-loss program for adults with overweight or obesity

Official title: Effectiveness of the Addition of Yoga to a Behavioral Weight Loss Intervention for Adults with Overweight or Obesity

Funded at University of Kansas Medical Center · NIH-11332631 · Data updated 2026-11-12

This trial compares whether adding regular yoga to a standard behavioral weight-loss program helps adults with overweight or obesity lose more weight over 12 months.

More Obesity research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Kansas Medical Center
NIH-funded
Lab location1 site (Kansas City, United States)
Project startApril 15, 2024
Project endFebruary 28, 2029
Funding year2026
Award (this year)$672,748
NIH project number5R01DK135735-03
Project IDNIH-11332631 on NIH RePORTER

Who could benefit from this research

Could help

Adults aged 21 and older with overweight or obesity who want to participate in a structured behavioral weight-loss program and can safely do physical activity are the ideal candidates.

Less likely to help

People under 21, those with normal weight, or those who cannot safely perform physical activity or yoga due to medical restrictions are unlikely to benefit from participating.

What this research studies

You would join a 12-month behavioral weight-loss program and be randomly assigned to follow either a yoga-based physical activity plan or a more standard aerobic activity plan (like brisk walking). Both groups follow the same diet and behavioral support, but the physical activity sessions and home practice differ. Study staff will take regular measurements such as weight, body composition, blood pressure, and mood, and you'll attend scheduled visits and activity sessions. The goal is to see whether yoga adds benefit beyond usual aerobic activity for long-term weight and health outcomes.

Why it matters

Potential benefit: If successful, adding yoga could help people lose more weight and improve body composition and blood pressure compared with standard aerobic activity in a behavioral program.

How similar studies have gone: Smaller or short-term studies and observational reports suggest yoga can help some health markers, but there are few long-term randomized trials directly comparing yoga to aerobic activity for weight loss.

Where this research is happening

  • University of Kansas Medical Center
    Kansas City, United States
    Active

Researchers

  • Principal investigator: Jakicic, John M — University of Kansas Medical Center
  • Study coordinator: Jakicic, John M

Related research

Other NIH-funded projects on the same topics.

  • Investigating how yoga can enhance weight loss in adults with obesity

    This study is looking at whether adding yoga to a weight loss program helps adults who are overweight or obese lose more weight and improve their health compared to just doing regular exercise, and you could help us learn more about this by joining!

    NIH research University of Kansas Medical Center · Kansas City, United States · NIH-11074671

  • Mindful Movement: guided imagery app to boost activity in adults with overweight or obesity

    A researcher-led plan to create and test an easy-to-use guided imagery app that helps adults with overweight or obesity stay more physically active.

    NIH research University of Tennessee Knoxville · Knoxville, United States · NIH-11430590

  • Tirzepatide for adults with alcohol use disorder and overweight or obesity

    This will see if the weight-loss medication tirzepatide can help adults with alcohol use disorder who are overweight or obese cut back on drinking and improve health measures.

    NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-11192379

  • Creating a program to help adults maintain weight loss and prevent regain

    This study is all about helping adults who have lost weight keep it off for good by offering personalized support and strategies that adapt to their needs, making it easier for them to manage their weight in the long run.

    NIH research University of Utah · Salt Lake City, United States · NIH-11083649

  • Evaluating Tirzepatide for treating alcohol use disorder and obesity in adults

    This study is looking at how well Tirzepatide, a new weight loss medication, can help adults who are overweight or obese and also have trouble with alcohol use, by seeing if it can reduce their drinking and help them lose weight for better health.

    NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-10999946

  • Effects of chemical exposure on weight loss in Hispanic children

    This study is looking at how certain chemicals in our environment might affect weight loss in overweight and obese Hispanic kids who are part of a community weight loss program, by checking their weight and health before and after a 10-week program.

    NIH research George Mason University · Fairfax, United States · NIH-10938574

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.