Adaptive support to reduce suicide risk after psychiatric hospitalization

Multimodality Adaptive Intervention for Post-Inpatient Hospitalization Suicide Risk Reduction

['FUNDING_R01'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-11104047

A personalized mobile and stepped support program to help adults manage suicidal thoughts during the high-risk months after leaving the hospital.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorMASSACHUSETTS GENERAL HOSPITAL (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-11104047 on ClinicalTrials.gov

What this research studies

If you join, you'll be monitored with brief mobile prompts that check how you're feeling and offer coping tools right when suicidal thoughts rise. The program adapts to your needs—some people receive extra single-session clinician or self-guided interventions if coping remains hard. The study uses a combination of real-time random prompts and stepped treatment decisions to find which mix of mobile and in-person supports works best. Follow-up focuses on the weeks and months after discharge when risk is highest.

Who could benefit from this research

Good fit: Adults (21 years and older) recently hospitalized for suicide risk who are being discharged and can use a smartphone-based program.

Not a fit: People under 21, those not recently hospitalized for suicide risk, or those without access to or ability to use a smartphone may not be eligible or benefit from this program.

Why it matters

Potential benefit: Could help people use coping strategies when they most need them and lower suicidal thinking and rehospitalization after discharge.

How similar studies have performed: Earlier small trials showed the just-in-time adaptive mobile approach was feasible and helped people use coping strategies, but combining it with stepped single-session supports is a newer approach now being tested at larger scale.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.