NIH-funded research R01 grant

ACT for HIV+ drinkers: a guided, phone-based program to help reduce hazardous alcohol use

Official title: Acceptance and Commitment Therapy for HIV+ hazardous drinkers: A randomized clinical trial

Funded at Syracuse University · NIH-11414874 · Data updated 2026-11-12

A phone-delivered Acceptance and Commitment Therapy program is being tested to help adults with HIV who drink Hazardously cut back on alcohol and improve health-related outcomes.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSyracuse University
NIH-funded
Lab location1 site (Syracuse, United States)
Project startSeptember 1, 2023
Project endAugust 31, 2028
Funding year2026
Award (this year)$533,656
NIH project number5R01AA030935-04
Project IDNIH-11414874 on NIH RePORTER

Who could benefit from this research

Could help

Adults with HIV who drink at hazardous levels and are open to a transdiagnostic, psychological-behavioral treatment approach.

Less likely to help

Individuals with HIV who do not have hazardous drinking or who are not willing to engage in a psychological-behavioral program may not benefit.

What this research studies

This project tests a telephone-based Acceptance and Commitment Therapy (ACT) program designed for adults with HIV who drink at hazardous levels. The goal is to reduce alcohol use by targeting psychological processes that underlie multiple mental health and substance use problems. Participants will be randomized to receive the ACT intervention or a comparison condition, with outcomes tracked over time in real-world HIV care settings. The approach builds on adapting ACT previously used for other behaviors, focusing on acceptance of internal experiences and commitment to health-oriented actions. If successful, the program could be scalable within HIV clinics to support adherence and overall well-being.

Why it matters

Potential benefit: If successful, patients could experience reduced hazardous drinking and improved HIV treatment outcomes and quality of life.

How similar studies have gone: ACT and transdiagnostic approaches have shown promise for related mental health and substance use problems, but full-scale RCTs for alcohol use among people with HIV are limited.

Where this research is happening

  • Syracuse University
    Syracuse, United States
    Active

Researchers

  • Principal investigator: Woolf-King, Sarah E — Syracuse University
  • Study coordinator: Woolf-King, Sarah E

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.