Acetaminophen's Impact on Children's Brain Development
Neurodevelopmental Effect of Acetaminophen Exposures
['FUNDING_R01'] · YALE UNIVERSITY · NIH-11131060
This project looks at how taking acetaminophen during pregnancy might affect a child's brain development and overall health as they grow up.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | YALE UNIVERSITY (nih funded) |
| Locations | 1 site (NEW HAVEN, UNITED STATES) |
| Trial ID | NIH-11131060 on ClinicalTrials.gov |
What this research studies
Many pregnant individuals use acetaminophen for pain and fever, but we don't fully understand its long-term effects on babies. This project will use health information from a large group of mothers and children in Denmark to explore this question. We will look at various aspects of children's development, including their milestones as infants, their behavior, motor skills, school performance, and mental health, up to age 18. Our goal is to provide clearer guidance on the safe use of acetaminophen during pregnancy.
Who could benefit from this research
Good fit: This research is focused on understanding past exposures in a large population, so it does not involve recruiting new patients for direct participation.
Not a fit: Patients seeking immediate treatment or direct medical advice for acetaminophen exposure will not receive direct benefit from this population-level data analysis.
Why it matters
Potential benefit: If successful, this work could offer important information to help pregnant individuals and their doctors make informed decisions about using acetaminophen, potentially improving children's health outcomes.
How similar studies have performed: While previous experimental studies suggest a link between prenatal acetaminophen exposure and brain development, this project aims to provide more comprehensive human data from a large population.
Where this research is happening
NEW HAVEN, UNITED STATES
- YALE UNIVERSITY — NEW HAVEN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LIEW, ZEYAN — YALE UNIVERSITY
- Study coordinator: LIEW, ZEYAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.