Accurate brain temperature imaging with advanced MRI
Absolute Brain Thermography using Multinuclear MRI
A new MRI technique will measure brain temperature more accurately for people with stroke or other acquired brain injuries.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11323607 on NIH RePORTER |
What this research studies
If you have a stroke or brain injury, this project aims to create MRI scans that map temperature throughout your brain so doctors can see local hot spots that standard checks miss. Researchers will use advanced multinuclear MRI sequences and special calibration steps to read temperature from different atomic signals and correct for magnetic field changes. The team plans to combine physics, imaging sequence design, and data processing to produce absolute, spatially resolved brain thermographs. The goal is a practical imaging tool that could be used in hospitals to identify regions at higher risk of damage.
Who could benefit from this research
Good fit: Ideal candidates would be people with acute ischemic stroke or other acquired brain injuries who can undergo MRI at a participating imaging center.
Not a fit: People without brain injury or those who cannot safely have an MRI (for example, due to incompatible implants) are unlikely to benefit directly from this work.
Why it matters
Potential benefit: If successful, this could help clinicians detect and target dangerously warm brain regions after stroke, potentially reducing tissue loss and improving outcomes.
How similar studies have performed: Earlier MR thermometry approaches have shown promise in research settings but faced technical limits in providing accurate absolute temperature maps, which this project aims to overcome.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Alon, Leeor — New York University School of Medicine
- Study coordinator: Alon, Leeor
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.