Access to advanced tools for determining 3D structures of biological molecules
Official title: GM/CA@APS: A Macromolecular Crystallography Resource
Funded at Uchicago Argonne, LLC · NIH-10929359 · Data updated 2026-11-12
This study is all about using advanced technology to help scientists figure out the 3D shapes of important biological molecules, which can lead to new treatments and therapies for patients.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Uchicago Argonne, LLC NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | September 30, 2020 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $4,227,715 |
| NIH project number | 5P30GM138396-05 |
| Project ID | NIH-10929359 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals with conditions that have a genetic or molecular basis, such as certain cancers or genetic disorders.
✕Less likely to help
Patients with conditions that are not related to molecular structures or do not involve biological macromolecules may not receive direct benefits from this research.
What this research studies
This research provides access to state-of-the-art macromolecular crystallography facilities that allow scientists to determine the 3D atomic structures of important biological molecules. By utilizing advanced X-ray beamlines, researchers can analyze samples quickly and accurately, which is crucial for understanding complex biological processes and diseases. The facility supports a wide range of experiments, including those that require precise energy adjustments for optimal data collection. Patients may benefit indirectly as this research contributes to the development of new treatments and therapies based on structural biology insights.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding diseases at the molecular level, potentially resulting in new therapeutic strategies.
How similar studies have gone: Other research utilizing macromolecular crystallography has shown significant success in elucidating molecular structures, leading to advancements in drug design and understanding of various diseases.
Where this research is happening
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Uchicago Argonne, LLC
Chicago, United States Active
Researchers
- Principal investigator: Fischetti, Robert F. — Uchicago Argonne, LLC
- Study coordinator: Fischetti, Robert F.
Related research
Other NIH-funded projects on the same topics.
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Improving techniques for studying protein structures using X-ray crystallography
This study is working on making it easier for scientists to look at protein structures using special X-ray techniques, so they can better understand how proteins affect our health and diseases.
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Training users on advanced crystallography technologies
This study is all about helping scientists learn how to use new tools and techniques to better understand the structures of large molecules, with friendly training sessions and hands-on workshops to boost their skills.
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Improving resources for macromolecular crystallography to solve biomedical problems
This study is all about making a special lab better for scientists who study the tiny structures of important biological molecules, so they can do their experiments more easily and effectively.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.