A vaccine to prevent lymphatic filariasis
A Vaccine for Lymphatic Filariasis, LFGuard™
This study is working on a new vaccine to help protect people from lymphatic filariasis, a disease caused by parasitic worms that affects many around the world, and it aims to provide lasting protection alongside current treatments.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pai Life Sciences, INC. NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10997344 on NIH RePORTER |
What this research studies
This research focuses on developing a vaccine for lymphatic filariasis (LF), a disease affecting millions worldwide. The vaccine aims to complement existing mass drug administration efforts by providing long-term protection against the disease, which is caused by parasitic worms. The approach involves creating a prophylactic vaccine that targets the adult parasites, addressing the limitations of current drug therapies that only treat existing infections. By preventing future infections, the vaccine could significantly reduce the incidence of LF in endemic regions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living in or traveling to endemic regions where lymphatic filariasis is prevalent.
Not a fit: Patients who are not at risk of lymphatic filariasis, such as those living in non-endemic areas, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a vaccine that prevents lymphatic filariasis, ultimately reducing the disease's prevalence and improving public health.
How similar studies have performed: Previous research has shown promise in developing vaccines for similar parasitic infections, indicating potential for success in this novel approach.
Where this research is happening
Seattle, United States
- Pai Life Sciences, INC. — Seattle, United States (Active)
Researchers
- Principal investigator: Carter, Darrick Albert — Pai Life Sciences, INC.
- Study coordinator: Carter, Darrick Albert
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.