NIH-funded research NIH-funded research

A UV Disinfection System for Catheters to Prevent Bloodstream Infections

Official title: Therapeutic UV Disinfection System to Prevent Catheter Related Bloodstream Infections (CRBSIs) in Patients with Peripherally Inserted Central Catheters (PICCs)

Funded at Puracath Medical, INC. · NIH-11126870 · Data updated 2026-11-12

This project is preparing a special ultraviolet light system to help keep central line catheters clean and prevent serious bloodstream infections in patients.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionPuracath Medical, INC.
NIH-funded
Lab location1 site (Newark, UNITED STATES)
Project startJuly 6, 2023
Project endJune 30, 2026
Funding year2025
Award (this year)$992,594
NIH project number5SB1AI174371-03
Project IDNIH-11126870 on NIH RePORTER

Who could benefit from this research

Could help

Patients who have Peripherally Inserted Central Catheters (PICCs) and are at risk for bloodstream infections would be the target beneficiaries of this technology.

Less likely to help

Patients without PICCs or other types of central venous catheters would not directly benefit from this specific disinfection system.

What this research studies

We are working to make a therapeutic system ready for widespread use that disinfects the connector on Peripherally Inserted Central Catheters (PICCs). This system uses ultraviolet light to eliminate harmful germs and biofilms, which are sticky layers of bacteria and fungi, by a very high percentage. The goal is to stop these germs from entering the bloodstream through the catheter and causing serious infections. This involves developing a special UV-transmissive connector and a handheld device with UV lights and sensors.

Why it matters

Potential benefit: If successful, this system could significantly reduce the risk of life-threatening catheter-related bloodstream infections for patients with PICCs.

How similar studies have gone: The needleless connector component of this system has already received initial FDA clearance, and the overall system performance was validated in a previous phase, indicating promising prior success.

Where this research is happening

  • Puracath Medical, INC.
    Newark, United States
    Active

Researchers

  • Principal investigator: Rasooly, Julia — Puracath Medical, INC.
  • Study coordinator: Rasooly, Julia

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.