A urine test to diagnose obstructive sleep apnea in children
Official title: UroMarker Test Panel for Obstructive Sleep Apnea
Funded at Pgxl Technologies, LLC · NIH-10919156 · Data updated 2026-11-12
This study is working on a simple urine test to help doctors quickly and easily find out if kids have obstructive sleep apnea, a condition that can affect their sleep and learning, making it easier for families to get the help they need.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pgxl Technologies, LLC NIH-funded |
| Lab location | 1 site (Louisville, United States) |
| Project start | September 20, 2024 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $301,224 |
| NIH project number | 1R44HL174221-01 |
| Project ID | NIH-10919156 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years who exhibit symptoms of obstructive sleep apnea or are at risk for the condition.
✕Less likely to help
Patients who do not have symptoms of obstructive sleep apnea or are older than 11 years may not benefit from this research.
What this research studies
This research focuses on developing a non-invasive urine-based test to diagnose obstructive sleep apnea (OSA) in children. OSA can cause serious health issues, including sleep disturbances and cognitive impairments, but current diagnostic methods are often invasive and expensive. The new test aims to provide a quicker and more accessible way to identify OSA, allowing for better monitoring and treatment of affected children. By using a multiplexed immunoassay, the researchers hope to screen a larger population effectively.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of obstructive sleep apnea in children, improving their overall health and quality of life.
How similar studies have gone: While there have been various approaches to diagnosing sleep apnea, this urine-based assay represents a novel method that has not been widely tested in children.
Where this research is happening
-
Pgxl Technologies, LLC
Louisville, United States Active
Researchers
- Principal investigator: Burns, Christopher Thomas — Pgxl Technologies, LLC
- Study coordinator: Burns, Christopher Thomas
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.