A universal influenza vaccine using a microneedle patch
Multivalent nanocluster universal influenza vaccine given by microneedle patch
This study is working on a new flu vaccine that could protect you from many different types of the flu virus, using a special patch that makes it easy to get the shot, and it will be tested in animals to see how well it works.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgia State University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10549821 on NIH RePORTER |
What this research studies
This research focuses on developing a universal influenza vaccine that can provide broad protection against various strains of the influenza virus. The approach involves creating multivalent nanoclusters that combine different influenza antigens, which are then delivered through a microneedle patch for easy administration. By targeting conserved proteins from both influenza A and B, the vaccine aims to induce a strong immune response that can protect against seasonal and pandemic strains. The research will involve testing this vaccine in laboratory animal models to evaluate its effectiveness.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who are at risk for influenza infections.
Not a fit: Patients who are not at risk for influenza or those with specific contraindications to vaccination may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a more effective and long-lasting influenza vaccine that reduces the need for annual vaccinations and protects against emerging strains.
How similar studies have performed: Other research has shown promise in developing universal influenza vaccines, but this specific approach using multivalent nanoclusters is relatively novel.
Where this research is happening
Atlanta, United States
- Georgia State University — Atlanta, United States (Active)
Researchers
- Principal investigator: Wang, Baozhong — Georgia State University
- Study coordinator: Wang, Baozhong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.