A trial to improve outcomes for older patients with lower extremity fractures.
Musculoskeletal Adaptive Platform Trial (MAPT)
This study is looking at a new way to test different surgeries for older adults who have broken their leg or ankle, to find out which treatments work best for helping them recover and get back on their feet.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10977920 on NIH RePORTER |
What this research studies
This research investigates a new approach to clinical trials called adaptive platform trials, which allows for the simultaneous testing of multiple treatments for older patients who have suffered lower extremity fractures. By comparing different surgical interventions, the trial aims to identify the most effective treatments while adapting to changes in patient needs and clinical practices. Patients aged 65 and older who are admitted with specific types of fractures will be the focus, and their outcomes will be assessed based on factors like mobility and overall health after surgery.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients aged 65 and older who have sustained a fracture of the lower extremity, pelvis, or acetabulum.
Not a fit: Patients who are younger than 65 or do not have fractures in the specified areas may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved surgical outcomes and recovery for older patients with fractures.
How similar studies have performed: Adaptive platform trials have shown promise in other areas of clinical research, indicating potential for success in this novel application.
Where this research is happening
Baltimore, United States
- University of Maryland Baltimore — Baltimore, United States (Active)
Researchers
- Principal investigator: O'hara, Nathan Noel — University of Maryland Baltimore
- Study coordinator: O'hara, Nathan Noel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.