A tool to measure how chronic pain affects daily activities
Official title: An Instrument to Assess the Functional Impact of Chronic Pain
Funded at Barron Associates, INC. · NIH-10479024 · Data updated 2026-11-12
This study is testing a new tool called KnowPain that helps understand how chronic pain affects your daily life by combining what you feel with data from special sensors, so we can find better ways to manage your pain.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Barron Associates, INC. NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project start | September 30, 2019 |
| Project end | August 31, 2025 |
| Funding year | 2022 |
| Award (this year) | $774,621 |
| NIH project number | 5R44NS113740-03 |
| Project ID | NIH-10479024 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing chronic pain that significantly impacts their daily activities.
✕Less likely to help
Patients with acute pain conditions or those not experiencing chronic pain may not benefit from this research.
What this research studies
This research focuses on developing a new instrument called KnowPain, which aims to objectively assess the functional impact of chronic pain on patients' daily lives. By combining subjective patient-reported outcomes with objective data collected through advanced biometric sensors, the study seeks to provide a comprehensive evaluation of how pain affects functionality. The instrument will measure various physiological parameters, such as motion, heart rate, and skin temperature, to generate precise scores reflecting functional impairment due to chronic pain. This innovative approach aims to improve pain management and treatment evaluation for patients suffering from chronic pain.
Why it matters
Potential benefit: If successful, this research could lead to more accurate assessments of chronic pain, ultimately improving treatment outcomes for patients.
How similar studies have gone: Other research has shown promise in using biometric assessments for pain evaluation, indicating that this approach could be effective.
Where this research is happening
-
Barron Associates, INC.
Charlottesville, United States Active
Researchers
- Principal investigator: Clark, Brian R — Barron Associates, INC.
- Study coordinator: Clark, Brian R
Related research
Other NIH-funded projects on the same topics.
-
Motor cortex tricks to ease chronic pain
A study in rodents and people tests whether non-invasive brain stimulation of the motor cortex can reduce chronic pain and how best to target it.
-
Human pain center study to map normal and migraine-trigeminal neurons
A large NIH-funded project will map and study the human trigeminal neurons involved in migraines to understand what changes in these cells during headache conditions.
-
Understanding human pain neurons to improve migraine care
Researchers are studying human pain-sensing neurons to uncover what makes migraine start and persist, with the goal of better treatments for people who experience migraines.
-
Whole Person Pain Algorithm to personalize chronic pain care
A new, evidence-based model helps explain why chronic low back pain affects people differently and could guide personalized diagnosis and treatment.
-
Understanding how to use pharmacogenomic testing to guide chronic pain care
This grant looks at how doctors who treat long‑term pain decide when and how to use genetic testing to tailor pain medicines for safer and more effective care.
-
Mindfulness and Self-Hypnosis for Pain in Older Adults
This grant tests non-drug ways like mindfulness and self-hypnosis to help people over 60 manage chronic pain.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.