A tool to map how brain structure and function relate to behavior
Official title: The Krackencoder: a multi-modal connectome fusion tool for brain-behavior mapping
Funded at Weill Medical Coll of Cornell Univ · NIH-11110795 · Data updated 2026-11-12
This study is exploring how different parts of the brain work together and affect our behavior, using a new tool to help understand these connections better, and it's for anyone interested in how brain activity relates to actions, whether they have a behavioral diagnosis or not.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | June 15, 2025 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $582,953 |
| NIH project number | 1R01MH137166-01A1 |
| Project ID | NIH-11110795 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adolescents and adults who exhibit a range of behavioral conditions or are healthy individuals interested in understanding brain-behavior relationships.
✕Less likely to help
Patients with severe cognitive impairments or those unable to undergo MRI scans may not benefit from this research.
What this research studies
This research focuses on understanding the complex relationships between brain structure, function, and behavior using advanced neuroimaging techniques. By developing a new computational tool called the Krakencoder, the project aims to integrate various types of brain connectivity data to create a more accurate model of how brain circuitry influences behavior. This tool will be validated across different individuals, including those with and without behavioral diagnoses, to ensure it captures individual differences effectively. The ultimate goal is to enhance our ability to predict behavior based on brain data, which could lead to better interventions and treatments.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prediction of behaviors based on brain connectivity, potentially informing better treatment strategies for various behavioral conditions.
How similar studies have gone: Previous research has shown promise in using neuroimaging to map brain-behavior relationships, but the Krakencoder represents a novel approach that aims to enhance accuracy and individual variability.
Where this research is happening
-
Weill Medical Coll of Cornell Univ
New York, United States Active
Researchers
- Principal investigator: Kuceyeski, Amy Frances — Weill Medical Coll of Cornell Univ
- Study coordinator: Kuceyeski, Amy Frances
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.