A tool to help patients and doctors make safer decisions about anticoagulant medications.
Official title: Implementation of DDInteract: A Shared-decision Making Tool for Anticoagulant Drug-Drug INTERACTions
Funded at University of Utah · NIH-10907428 · Data updated 2026-11-12
This study is testing a new tool called DDInteract that helps patients and doctors work together to avoid dangerous drug interactions for people taking blood thinners like warfarin and DOACs, making it easier to understand the risks and benefits of their treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project start | August 15, 2023 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $999,956 |
| NIH project number | 5R18HS029300-02 |
| Project ID | NIH-10907428 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients who are prescribed anticoagulants and have multiple comorbidities requiring additional medications.
✕Less likely to help
Patients who are not on anticoagulant therapy or those without multiple medication needs may not benefit from this research.
What this research studies
This research focuses on developing and implementing a shared-decision making tool called DDInteract, which aims to reduce the risk of harmful drug-drug interactions (DDIs) for patients taking anticoagulants like warfarin and direct-acting anticoagulants (DOACs). The tool integrates with existing electronic health record (EHR) systems, providing personalized alerts and information to both prescribers and patients about potential interactions. By using an implementation science approach, the project seeks to ensure that this tool is effectively adopted in clinical practice, allowing for better communication and understanding of the risks and benefits associated with anticoagulant therapy. This collaborative effort aims to empower patients and healthcare providers to make informed decisions together.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risk of bleeding complications in patients taking anticoagulants by improving decision-making around medication management.
How similar studies have gone: Other research has shown success with similar decision-making tools in improving patient safety and medication management, indicating a promising approach.
Where this research is happening
-
University of Utah
Salt Lake City, United States Active
Researchers
- Principal investigator: Malone, Daniel C — University of Utah
- Study coordinator: Malone, Daniel C
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.