A test to diagnose and predict severe dengue infections quickly.
Simultaneous Diagnosis of Dengue and Prognosis of Severe Dengue with a Single Point-of-Care Test
This study is working on a quick test that can help doctors find out if someone has dengue and if they might get very sick from it, so they can start treatment sooner and help save lives.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mabdx, INC. NIH-funded |
| Lab location | 1 site (Eugene, United States) |
| Project ID | NIH-10475305 on NIH RePORTER |
What this research studies
This research focuses on developing a rapid point-of-care test that can simultaneously diagnose dengue infections and predict the likelihood of progression to severe dengue. By identifying patients at risk of severe disease early, healthcare providers can initiate timely interventions that significantly reduce mortality rates. The test aims to leverage the understanding of antibody responses to different dengue virus serotypes, which can complicate the disease's progression. This innovative approach seeks to improve patient outcomes through better decision-making in clinical settings.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals presenting with symptoms of dengue fever, particularly those at risk of developing severe dengue.
Not a fit: Patients who have already been diagnosed with severe dengue or those without symptoms of dengue fever may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a significant reduction in mortality and morbidity associated with severe dengue infections.
How similar studies have performed: Previous research has shown promise in developing diagnostic tests for dengue, but this specific approach to simultaneous diagnosis and prognosis is relatively novel.
Where this research is happening
Eugene, United States
- Mabdx, INC. — Eugene, United States (Active)
Researchers
- Principal investigator: Marusich, Michael F — Mabdx, INC.
- Study coordinator: Marusich, Michael F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.