A system to improve methadone treatment for opioid use disorder

Therapeutic Monitoring System (TMS)

NIH-funded research Cari Health, INC. · NIH-10786206

This study is looking at a new way to help people with opioid use disorder by making it easier for them to get their methadone treatment, especially for those who have a hard time going to daily appointments, so they can feel better and have more freedom in their lives.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionCari Health, INC. NIH-funded
Lab location1 site (San Diego, United States)
Project IDNIH-10786206 on NIH RePORTER

What this research studies

This research focuses on developing a Therapeutic Monitoring System (TMS) to enhance the treatment of opioid use disorder (OUD) with methadone. It aims to address the challenges faced by patients who must attend opioid treatment programs (OTPs) daily for their medication, which can be particularly burdensome for those in rural or low-income areas. By exploring the potential for longer take-home doses of methadone, the research seeks to improve patient compliance and satisfaction while reducing stigma associated with OUD treatment. The approach includes evaluating the impact of relaxed federal policies on treatment engagement and medication misuse.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals receiving methadone treatment for opioid use disorder, particularly those facing barriers to daily clinic visits.

Not a fit: Patients who are not currently receiving methadone treatment or those with severe complications from opioid use disorder may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more flexible and accessible treatment options for patients with opioid use disorder, improving their overall quality of life.

How similar studies have performed: Previous research during the COVID-19 pandemic has shown positive outcomes with similar approaches, indicating potential for success in this area.

Where this research is happening

San Diego, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.