A system for recording brain activity in freely moving mice
ONIX: A Neural Acquisition System for Unencumbered, Closed-Loop Recordings in Small, Freely Moving Animals
This study is testing a new device called ONIX that helps scientists record brain activity in mice while they move around freely, which could help us learn more about how the brain works in relation to behavior and thinking.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Open Ephys, INC NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project ID | NIH-10690059 on NIH RePORTER |
What this research studies
This research focuses on developing a new neural recording system called ONIX, which allows for high-quality brain activity recordings in mice while they move freely in their environment. The system aims to minimize the impact of recording devices on the animals' natural behaviors, enabling longer and more complex studies of brain function. By using head-mounted devices that track the position and orientation of the mice, the ONIX system ensures that recordings are accurate without hindering the animals' movements. This innovative approach could lead to significant advancements in our understanding of neural processes related to behavior and cognition.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with neurological disorders or those interested in the underlying mechanisms of brain function.
Not a fit: Patients with conditions unrelated to neurological function or those who do not have access to advanced research facilities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of brain function and lead to improved treatments for neurological conditions.
How similar studies have performed: Other research has shown success with similar neural recording technologies, indicating a promising avenue for further exploration.
Where this research is happening
Cambridge, United States
- Open Ephys, INC — Cambridge, United States (Active)
Researchers
- Principal investigator: Newman, Jonathan — Open Ephys, INC
- Study coordinator: Newman, Jonathan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.