NIH-funded research Sbir 2 grant

A system for real-time monitoring of radiation therapy delivery

Official title: DoseRT™ : A Non-Contact Optical Patient and Beam Dosimetry System for Continuous in vivo Radiotherapy Verification

Funded at Doseoptics, LLC · NIH-11115803 · Data updated 2026-11-12

This study is testing a new, easy-to-use system called DoseRT™ that helps make sure radiation therapy for cancer is delivered accurately and safely, so patients can feel more confident about their treatment and have a lower risk of side effects.

More Radiotherapy research and trials

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionDoseoptics, LLC
NIH-funded
Lab location1 site (Lebanon, United States)
Project startAugust 1, 2018
Project endMay 31, 2027
Funding year2025
Award (this year)$998,974
NIH project number5R44CA232879-05
Project IDNIH-11115803 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients receiving radiation therapy for cancer treatment.

Less likely to help

Patients who are not undergoing radiation therapy or those receiving alternative cancer treatments may not benefit from this research.

What this research studies

This research focuses on developing a non-contact optical system called DoseRT™ that continuously verifies the delivery of radiation therapy during treatment. By utilizing Cherenkov imaging technology, the system captures real-time data on how radiation is administered to ensure precision and minimize the risk of side effects. This innovative approach aims to enhance the safety and effectiveness of radiation therapy, which is a common treatment for various cancers. Patients undergoing radiation therapy may benefit from improved treatment accuracy and reduced chances of secondary cancers.

Why it matters

Potential benefit: If successful, this research could significantly improve the safety and effectiveness of radiation therapy for cancer patients.

How similar studies have gone: Similar approaches using imaging technologies in radiation therapy have shown promise, indicating potential for success in this novel application.

Where this research is happening

  • Doseoptics, LLC
    Lebanon, United States
    Active

Researchers

  • Principal investigator: Ware, William — Doseoptics, LLC
  • Study coordinator: Ware, William

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.