A system for precise navigation of brain stimulation techniques

Near real-time system for high-resolution computationalTMS navigation

['FUNDING_R01'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-10993678

This study is working on making Transcranial Magnetic Stimulation (TMS) better for people with depression by using new technology to more accurately target the areas of the brain that need help, so you can get a more effective and personalized treatment.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorMASSACHUSETTS GENERAL HOSPITAL (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-10993678 on ClinicalTrials.gov

What this research studies

This research focuses on improving Transcranial Magnetic Stimulation (TMS), a non-invasive method used to modulate brain activity, particularly for conditions like major depressive disorder. The project aims to develop a near real-time system that accurately targets specific brain regions by utilizing advanced computational techniques to model electric field distributions induced by TMS. By enhancing the precision of TMS delivery, the research seeks to optimize treatment outcomes for patients suffering from depression. Participants may experience a more effective and tailored approach to their TMS therapy.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with major depressive disorder or treatment-resistant depression who are considering TMS therapy.

Not a fit: Patients with non-depressive conditions or those who do not qualify for TMS therapy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective TMS treatments for patients with depression, improving their overall mental health outcomes.

How similar studies have performed: Previous research has shown promising results in enhancing TMS efficacy through improved targeting methods, indicating that this approach has potential for success.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.