A software tool to improve heart failure treatment outcomes
Software Tool for Optimization of CRT
['FUNDING_SBIR_1'] · 3DT HOLDINGS, LLC · NIH-10915234
This study is testing a new software tool that helps doctors personalize heart treatment for patients with heart failure, especially those with a specific heart condition called left bundle branch block, to make sure more people benefit from the therapy.
Quick facts
| Phase | ['FUNDING_SBIR_1'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | 3DT HOLDINGS, LLC (nih funded) |
| Locations | 1 site (SAN DIEGO, UNITED STATES) |
| Trial ID | NIH-10915234 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a software tool designed to optimize cardiac resynchronization therapy (CRT) for patients with heart failure, particularly those with left bundle branch block. The tool aims to enhance the effectiveness of CRT by using computational models to tailor treatment strategies based on individual patient characteristics. By analyzing factors such as lead positioning and timing of stimulation, the software seeks to reduce the number of patients who do not respond to CRT. This approach is particularly relevant for patients with ischemic cardiomyopathy, who often experience higher rates of non-response.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with heart failure who have left bundle branch block and are candidates for cardiac resynchronization therapy.
Not a fit: Patients without heart failure or those who do not have left bundle branch block may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve treatment outcomes for heart failure patients undergoing CRT, potentially reducing mortality rates.
How similar studies have performed: Previous research has shown promise in using computational models for optimizing cardiac therapies, indicating that this approach could be effective.
Where this research is happening
SAN DIEGO, UNITED STATES
- 3DT HOLDINGS, LLC — SAN DIEGO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GUCCIONE, JULIUS MATTEO — 3DT HOLDINGS, LLC
- Study coordinator: GUCCIONE, JULIUS MATTEO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Bundle Branch disorder