A service to determine how drugs work at a molecular level
Official title: eMOA: A Multi-Omic Service for Mechanism of Action Determination in Drug Screening
Funded at Eclipse Bioinnovations INC · NIH-11111218 · Data updated 2026-11-12
This study is working on a new way to understand how drugs work in our cells, which could help make drug development quicker and cheaper, ultimately leading to better treatments for patients like you.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Eclipse Bioinnovations INC NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project start | July 1, 2024 |
| Project end | December 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $1,148,465 |
| NIH project number | 4R44GM154583-02 |
| Project ID | NIH-11111218 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that require new therapeutic interventions or those involved in clinical trials for drug testing.
✕Less likely to help
Patients who are not currently seeking new treatments or those with conditions that are not targeted by the drugs being investigated may not benefit from this research.
What this research studies
This research focuses on developing a multi-omic service that helps identify the mechanisms by which drugs affect cellular functions. By utilizing advanced techniques such as transcriptomics and proteomics, the project aims to streamline the drug development process, making it faster and more cost-effective. Patients may benefit from this research as it seeks to enhance the understanding of drug actions, potentially leading to more effective therapies. The approach combines various biological assays to provide a comprehensive view of how drugs interact with cellular processes.
Why it matters
Potential benefit: If successful, this research could lead to faster and more effective drug development, resulting in better treatment options for patients.
How similar studies have gone: Other research has shown success with similar multi-omic approaches in drug development, indicating a promising avenue for future advancements.
Where this research is happening
-
Eclipse Bioinnovations INC
San Diego, United States Active
Researchers
- Principal investigator: Shishkin, Alexander a — Eclipse Bioinnovations INC
- Study coordinator: Shishkin, Alexander a
Related research
Other NIH-funded projects on the same topics.
-
Multi-omic tool to reveal how drugs work
A new software-enabled service helps scientists quickly figure out exactly how potential drugs work on human biology using multiple biological readouts.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.