NIH-funded research Sbir 2 grant

A service to determine how drugs work at a molecular level

Official title: eMOA: A Multi-Omic Service for Mechanism of Action Determination in Drug Screening

Funded at Eclipse Bioinnovations INC · NIH-11111218 · Data updated 2026-11-12

This study is working on a new way to understand how drugs work in our cells, which could help make drug development quicker and cheaper, ultimately leading to better treatments for patients like you.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionEclipse Bioinnovations INC
NIH-funded
Lab location1 site (San Diego, United States)
Project startJuly 1, 2024
Project endDecember 31, 2026
Funding year2025
Award (this year)$1,148,465
NIH project number4R44GM154583-02
Project IDNIH-11111218 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals with conditions that require new therapeutic interventions or those involved in clinical trials for drug testing.

Less likely to help

Patients who are not currently seeking new treatments or those with conditions that are not targeted by the drugs being investigated may not benefit from this research.

What this research studies

This research focuses on developing a multi-omic service that helps identify the mechanisms by which drugs affect cellular functions. By utilizing advanced techniques such as transcriptomics and proteomics, the project aims to streamline the drug development process, making it faster and more cost-effective. Patients may benefit from this research as it seeks to enhance the understanding of drug actions, potentially leading to more effective therapies. The approach combines various biological assays to provide a comprehensive view of how drugs interact with cellular processes.

Why it matters

Potential benefit: If successful, this research could lead to faster and more effective drug development, resulting in better treatment options for patients.

How similar studies have gone: Other research has shown success with similar multi-omic approaches in drug development, indicating a promising avenue for future advancements.

Where this research is happening

  • Eclipse Bioinnovations INC
    San Diego, United States
    Active

Researchers

  • Principal investigator: Shishkin, Alexander a — Eclipse Bioinnovations INC
  • Study coordinator: Shishkin, Alexander a

Related research

Other NIH-funded projects on the same topics.

  • Multi-omic tool to reveal how drugs work

    A new software-enabled service helps scientists quickly figure out exactly how potential drugs work on human biology using multiple biological readouts.

    NIH research Eclipse Bioinnovations INC · San Diego, United States · NIH-11258908

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.