A resource for analyzing the structure of DNA and RNA
Official title: X3DNA-DSSR: a resource for structural bioinformatics of nucleic acids
Funded at Columbia Univ New York Morningside · NIH-10868162 · Data updated 2026-11-12
This study is all about a helpful tool that makes it easier for scientists to understand the shapes and interactions of DNA and RNA, which could eventually lead to better treatments for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia Univ New York Morningside NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 20, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $522,974 |
| NIH project number | 1R24GM153869-01 |
| Project ID | NIH-10868162 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals with genetic disorders or those interested in the molecular basis of diseases.
✕Less likely to help
Patients with conditions unrelated to genetic structures or those not involved in research may not receive direct benefits from this research.
What this research studies
X3DNA-DSSR is a resource designed to enhance the understanding of nucleic acids by providing advanced tools for structural bioinformatics. It builds on previous successful programs to analyze both canonical and non-canonical DNA and RNA structures, as well as their interactions with proteins. This resource is user-friendly and aims to maintain high accessibility for researchers worldwide, allowing them to analyze complex biological data effectively. Patients may benefit indirectly through advancements in understanding genetic structures that could lead to improved treatments.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for genetic conditions.
How similar studies have gone: Previous research in structural bioinformatics has shown significant success, indicating that this approach is likely to yield valuable insights.
Where this research is happening
-
Columbia Univ New York Morningside
New York, United States Active
Researchers
- Principal investigator: Lu, Xiang-Jun — Columbia Univ New York Morningside
- Study coordinator: Lu, Xiang-Jun
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.