A regional center for stroke trials in New England

Who could benefit from this research

What this research studies

This research involves the continuation of the New England Regional Coordinating Center for the NINDS Stroke Trials Network, which integrates a team of hospitals in the Greater Boston Area and surrounding regions. The center aims to enhance stroke care by participating in clinical trials that evaluate new treatments and interventions for stroke patients. With a strong network of over 30 hospitals, the center is well-equipped to recruit participants and conduct high-quality research in stroke neurology. The team consists of experienced clinical investigators from various specialties, ensuring comprehensive care and research capabilities.

Why it matters

Where this research is happening

• Massachusetts General Hospital
  Boston, United States Active

Researchers

• Principal investigator: Singhal, Aneesh B — Massachusetts General Hospital
• Study coordinator: Singhal, Aneesh B

Related research

Other NIH-funded projects on the same topics.

• Stroke prevention with hydroxyurea for children with sickle cell anemia in Nigeria

  A multinational, patient-facing study tests whether hydroxyurea can safely prevent first strokes in Nigerian children with sickle cell anemia.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11629280

• Music-powered tools to boost blood pressure and stroke prevention for Nigerian youth and their older caregivers

  This project uses popular music to help Nigerian youths and their older family members start and stick to blood pressure and stroke prevention habits.

  NIH research Washington University · Saint Louis, United States · NIH-11627865

• Determinants of Post-Stroke Cognitive Outcomes and Vascular Effects on Recovery

  A large, multi-site effort aims to understand why some stroke survivors develop long-term cognitive problems and dementia, and how vascular health and pre-existing brain changes influence recovery.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11621895

• LRP1 controls NSC movement and stroke recovery

  This NIH grant studies how a brain receptor called LRP1 helps neural stem cells move to stroke injuries and support recovery in adults.

  NIH research University of Texas Hlth Science Center · San Antonio, United States · NIH-11617802

• BBB Dysfunction after Stroke and Risk for Dementia

  A study at Stanford will look at whether inflammation after a stroke leads to leaky blood vessels and later dementia, by following stroke survivors and comparing them with people without stroke.

  NIH research Stanford University · Stanford, United States · NIH-11610460

• Improving blood flow after stroke by breaking down NETs

  Aims to see if breaking down neutrophil extracellular traps (NETs) after an ischemic stroke can improve blood flow and reduce brain injury in patients.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11606640

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.