A rapid test to detect lymphatic filariasis infections
Official title: Ultrasensitive, High-Specificity Rapid Test to Support the End-Game of the Global Program to Eliminate Lymphatic Filariasis
Funded at Big Eye Diagnostics, INC. · NIH-11083346 · Data updated 2026-11-12
This study is working on a new, easy-to-use test that can quickly and accurately detect lymphatic filariasis, a disease caused by a parasite, to help communities monitor and manage the disease better, especially after treatment programs.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Big Eye Diagnostics, INC. NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project start | May 1, 2022 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $852,688 |
| NIH project number | 4R44AI170131-02 |
| Project ID | NIH-11083346 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals living in regions where lymphatic filariasis is endemic and who may be at risk of infection.
✕Less likely to help
Patients who do not reside in endemic areas or who have already been treated for lymphatic filariasis may not benefit from this research.
What this research studies
This research focuses on developing a highly sensitive and specific lateral flow assay (LFA) for the detection of lymphatic filariasis (LF), a neglected tropical disease caused by a parasitic worm. The test aims to meet the World Health Organization's requirements for surveillance activities, allowing for early detection of infections and improved monitoring after mass drug administration programs. By utilizing a field-deployable and cost-effective approach, the test will enhance the ability to assess transmission and treatment outcomes in affected populations.
Why it matters
Potential benefit: If successful, this research could lead to more effective surveillance and control of lymphatic filariasis, ultimately reducing the disease's prevalence and improving patient outcomes.
How similar studies have gone: Previous research has shown success with similar diagnostic approaches, but this specific test aims to address gaps in current surveillance methods for lymphatic filariasis.
Where this research is happening
-
Big Eye Diagnostics, INC.
San Diego, United States Active
Researchers
- Principal investigator: Biamonte, Marco Antonio — Big Eye Diagnostics, INC.
- Study coordinator: Biamonte, Marco Antonio
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.