A rapid test for detecting HIV-1 using CRISPR technology

CRISPR-Cas13-based rapid HIV-1 test

NIH-funded research Rice University · NIH-11009060

This study is working on a simple and fast way for people to test themselves for HIV-1 using a new technology that can detect the virus in blood or saliva without needing special equipment, making it easier for everyone to get tested and find out their status early.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionRice University NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-11009060 on NIH RePORTER

What this research studies

This research aims to develop a quick and sensitive test for HIV-1 that can be performed without specialized equipment. It focuses on using CRISPR-Cas13 technology to detect the virus in blood or saliva, making it easier for individuals to test themselves. The test is designed to be shelf-stable and user-friendly, addressing the limitations of current testing methods that require complex procedures and refrigeration. By simplifying the testing process, this research hopes to improve early detection of HIV, especially during acute infections.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals at risk of HIV infection or those who may have recently been exposed to the virus.

Not a fit: Patients who are already diagnosed with HIV and are receiving effective antiretroviral therapy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a more accessible and accurate method for early detection of HIV-1, potentially reducing transmission rates.

How similar studies have performed: Other research has shown promise in using CRISPR technology for rapid diagnostics, indicating potential success for this novel approach.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virusacute infection
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.