A rapid test for detecting HIV-1 using CRISPR technology
Official title: CRISPR-Cas13-based rapid HIV-1 test
Funded at Rice University · NIH-11009060 · Data updated 2026-11-12
This study is working on a simple and fast way for people to test themselves for HIV-1 using a new technology that can detect the virus in blood or saliva without needing special equipment, making it easier for everyone to get tested and find out their status early.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rice University NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | January 24, 2023 |
| Project end | December 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $449,074 |
| NIH project number | 5R61AI167037-03 |
| Project ID | NIH-11009060 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at risk of HIV infection or those who may have recently been exposed to the virus.
✕Less likely to help
Patients who are already diagnosed with HIV and are receiving effective antiretroviral therapy may not benefit from this research.
What this research studies
This research aims to develop a quick and sensitive test for HIV-1 that can be performed without specialized equipment. It focuses on using CRISPR-Cas13 technology to detect the virus in blood or saliva, making it easier for individuals to test themselves. The test is designed to be shelf-stable and user-friendly, addressing the limitations of current testing methods that require complex procedures and refrigeration. By simplifying the testing process, this research hopes to improve early detection of HIV, especially during acute infections.
Why it matters
Potential benefit: If successful, this research could provide a more accessible and accurate method for early detection of HIV-1, potentially reducing transmission rates.
How similar studies have gone: Other research has shown promise in using CRISPR technology for rapid diagnostics, indicating potential success for this novel approach.
Where this research is happening
-
Rice University
Houston, United States Active
Researchers
- Principal investigator: Lillehoj, Peter B — Rice University
- Study coordinator: Lillehoj, Peter B
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.