A quick test for managing bleeding and strokes in patients on blood thinners
Official title: 5-Minute Point-of-Care Anti-Factor Xa Test for Emergent Patient Management
Funded at DNA Medicine Institute · NIH-11252219 · Data updated 2026-11-12
This study is working on a quick 5-minute test that helps doctors check the blood levels of patients taking certain blood thinners, so they can make fast and better treatment decisions during emergencies like bleeding or strokes.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | DNA Medicine Institute NIH-funded |
| Lab location | 1 site (Cambridge, UNITED STATES) |
| Project start | September 10, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $50,000 |
| NIH project number | 3R44HL170817-01A1S1 |
| Project ID | NIH-11252219 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients who are currently taking direct oral anticoagulants and may experience bleeding or acute ischemic strokes.
✕Less likely to help
Patients who are not on direct oral anticoagulants or those who do not present with bleeding or stroke symptoms may not benefit from this research.
What this research studies
This research aims to develop a rapid, 5-minute point-of-care test that measures anti-factor Xa levels and hemoglobin in patients who are on direct oral anticoagulants (DOACs). The test will help healthcare providers make immediate decisions regarding treatment options during emergencies, such as bleeding episodes or strokes. By providing timely information about a patient's anticoagulant levels, the test can guide the use of specific treatments like andexanet alfa for bleeding or thrombolytics for acute ischemic strokes. This innovative approach seeks to enhance patient management in emergency settings, ultimately improving outcomes for those affected by anticoagulant-related complications.
Why it matters
Potential benefit: If successful, this research could significantly improve emergency management for patients on anticoagulants, leading to faster and more effective treatment during critical situations.
How similar studies have gone: Other research has shown promise in developing rapid point-of-care tests for anticoagulant management, indicating that this approach has potential for success.
Where this research is happening
-
DNA Medicine Institute
Cambridge, United States Active
Researchers
- Principal investigator: Chan, Eugene Yan-Ho — DNA Medicine Institute
- Study coordinator: Chan, Eugene Yan-Ho
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.