A quick test for detecting HPV DNA linked to cervical cancer.
Official title: Point of Care HPV 16/18/45 DNA Test for Cervical Cancer
Funded at Crosslife Technologies, INC. · NIH-10930943 · Data updated 2026-11-12
This study is working on a quick and easy test that can detect certain types of HPV linked to cervical cancer, so that people can get results in under 30 minutes without needing a lab, making it especially helpful for those in areas with limited access to traditional testing.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Crosslife Technologies, INC. NIH-funded |
| Lab location | 1 site (Carlsbad, United States) |
| Project start | September 22, 2023 |
| Project end | February 28, 2026 |
| Funding year | 2025 |
| Award (this year) | $994,439 |
| NIH project number | 5R44CA250663-03 |
| Project ID | NIH-10930943 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women who are at risk for cervical cancer and may benefit from rapid HPV testing.
✕Less likely to help
Patients who have already been diagnosed with cervical cancer or those who do not have HPV types 16, 18, or 45 may not benefit from this research.
What this research studies
This research focuses on developing a rapid point-of-care test that can detect HPV types 16, 18, and 45, which are associated with cervical cancer. The test aims to provide results in under 30 minutes, making it suitable for use in non-laboratory settings and by non-technical personnel. By utilizing a novel chemical reaction, the test promises high sensitivity and specificity similar to existing laboratory assays, but with the convenience of a simple paper-strip readout. This approach addresses the need for effective cervical cancer screening, especially in developing countries where access to traditional testing may be limited.
Why it matters
Potential benefit: If successful, this research could significantly improve early detection of cervical cancer, potentially saving lives through timely intervention.
How similar studies have gone: Previous research has shown promise in developing point-of-care tests for HPV, indicating that this approach has potential for success.
Where this research is happening
-
Crosslife Technologies, INC.
Carlsbad, United States Active
Researchers
- Principal investigator: Cho, Hyundae — Crosslife Technologies, INC.
- Study coordinator: Cho, Hyundae
Related research
Other NIH-funded projects on the same topics.
-
Community and digital tools to reduce HPV and cervical cancer burden
A nurse or health team will test a community-based, digital strategy to help girls and young women, especially in rural areas, get HPV vaccination and cervical cancer prevention services.
-
Community and digital tools to reduce HPV and cervical cancer in women with HIV
A community- and digital-technology program aims to help girls and young women, including those with HIV, get more HPV vaccination and cervical cancer prevention services.
-
mSaada: a mobile tool to boost cervical cancer screening in western Kenya
A mobile app helps community health volunteers manage cervical cancer screening tasks and follow-up for women in low-resource areas.
-
Globally useful predictor for cervical cancer treatment response
This project aims to develop a simple predictive signature to personalize treatment for locally advanced cervical cancer using easy tests and imaging.
-
HPV self-collection in HIV care to screen for cervical cancer in Ethiopia
A patient-centered program tests a simple HPV self-collection approach within HIV clinics in Ethiopia to help detect cervical cancer earlier.
-
Hybrid approach to boost cervical cancer screening in Uganda
A tested, community-driven program helps Ugandan women encourage their peers to get free VIA cervical cancer screening.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.