A Quick and Sensitive Test for Opioids and Other Substances
Official title: Bench-top Reader and Aptamer-based Assay for Rapid, High-sensitivity Drug/Opiate Detection
Funded at Base Pair Biotechnologies, INC. · NIH-11177780 · Data updated 2026-11-12
This project aims to create a fast and highly sensitive test to detect opioids and other important substances in samples like urine.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Base Pair Biotechnologies, INC. NIH-funded |
| Lab location | 1 site (Pearland, United States) |
| Project start | September 15, 2023 |
| Project end | July 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $746,175 |
| NIH project number | 5R44EB034614-03 |
| Project ID | NIH-11177780 on NIH RePORTER |
Who could benefit from this research
✓Could help
This research is developing a diagnostic tool, so it doesn't directly involve patient participation, but its results could benefit anyone needing rapid drug or substance detection, such as those at risk of overdose or requiring therapeutic drug monitoring.
✕Less likely to help
Patients who do not require rapid drug detection or monitoring of specific small molecules would not directly benefit from this particular technology development.
What this research studies
The United States is facing a serious opioid crisis, and there's a growing need for quick and accurate ways to detect these drugs, as well as other important substances like therapeutic medicines or environmental contaminants. This project is developing a new bench-top device and a simple, three-step testing method that can quickly identify and measure these substances with very high sensitivity. The goal is to make a user-friendly system that can detect drugs or their byproducts in urine, potentially even in remote or field settings.
Why it matters
Potential benefit: If successful, this technology could provide a rapid and accurate way to detect drug use, monitor therapeutic drug levels, and identify harmful environmental contaminants, helping to save lives and improve public health.
How similar studies have gone: While other drug detection methods exist, this project aims to develop a novel, highly sensitive, and user-friendly bench-top system with a unique assay methodology.
Where this research is happening
-
Base Pair Biotechnologies, INC.
Pearland, United States Active
Researchers
- Principal investigator: Jackson, George W — Base Pair Biotechnologies, INC.
- Study coordinator: Jackson, George W
Related research
Other NIH-funded projects on the same topics.
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Measuring how well patients stick to HIV treatment using new sensors
This study is testing new sensors that can help track how well people with HIV are sticking to their medication routine, specifically with tenofovir, so that patients can get real-time feedback and improve their health.
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A new method for quickly and accurately detecting drugs and opioids.
This study is working on a new device that can quickly and accurately detect drugs like opioids in different samples, which could help doctors and communities tackle the opioid crisis more effectively.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.