A Quick and Sensitive Test for Opioids and Other Substances

Bench-top Reader and Aptamer-based Assay for Rapid, High-sensitivity Drug/Opiate Detection

NIH-funded research Base Pair Biotechnologies, INC. · NIH-11177780

This project aims to create a fast and highly sensitive test to detect opioids and other important substances in samples like urine.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionBase Pair Biotechnologies, INC. NIH-funded
Lab location1 site (Pearland, United States)
Project IDNIH-11177780 on NIH RePORTER

What this research studies

The United States is facing a serious opioid crisis, and there's a growing need for quick and accurate ways to detect these drugs, as well as other important substances like therapeutic medicines or environmental contaminants. This project is developing a new bench-top device and a simple, three-step testing method that can quickly identify and measure these substances with very high sensitivity. The goal is to make a user-friendly system that can detect drugs or their byproducts in urine, potentially even in remote or field settings.

Who could benefit from this research

Good fit: This research is developing a diagnostic tool, so it doesn't directly involve patient participation, but its results could benefit anyone needing rapid drug or substance detection, such as those at risk of overdose or requiring therapeutic drug monitoring.

Not a fit: Patients who do not require rapid drug detection or monitoring of specific small molecules would not directly benefit from this particular technology development.

Why it matters

Potential benefit: If successful, this technology could provide a rapid and accurate way to detect drug use, monitor therapeutic drug levels, and identify harmful environmental contaminants, helping to save lives and improve public health.

How similar studies have performed: While other drug detection methods exist, this project aims to develop a novel, highly sensitive, and user-friendly bench-top system with a unique assay methodology.

Where this research is happening

Pearland, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.