A program to prevent diabetes in childhood cancer survivors
PreDM: An adaptive, open-label, pilot intervention trial for diabetes prevention
This study is looking for childhood cancer survivors to join a program that helps them make healthy lifestyle changes and possibly take medication to lower their chances of getting diabetes, while keeping an eye on their health and blood sugar levels.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | St. Jude Children's Research Hospital NIH-funded |
| Lab location | 1 site (Memphis, United States) |
| Project ID | NIH-10668457 on NIH RePORTER |
What this research studies
This research focuses on childhood cancer survivors who are at a higher risk of developing diabetes compared to their siblings. It aims to implement an adaptive, open-label intervention that includes lifestyle changes and possibly medication to prevent the onset of diabetes. Participants will be monitored for their glucose levels and overall health to assess the effectiveness of the intervention. The study seeks to understand how to best support these survivors in managing their health and reducing their risk of diabetes.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 18 to 45 who are childhood cancer survivors and may be prediabetic.
Not a fit: Patients who are not childhood cancer survivors or those who do not have prediabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risk of diabetes and related health complications in childhood cancer survivors.
How similar studies have performed: Previous studies have shown success in diabetes prevention among the general population using similar lifestyle interventions and pharmacologic therapies.
Where this research is happening
Memphis, United States
- St. Jude Children's Research Hospital — Memphis, United States (Active)
Researchers
- Principal investigator: Dixon, Stephanie Berry — St. Jude Children's Research Hospital
- Study coordinator: Dixon, Stephanie Berry
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.