NIH-funded research NIH-funded research

A program to help people with knee osteoarthritis exercise more effectively

Official title: STepped Exercise Program for Knee Osteoarthritis: The STEP-KOA Study

Funded at Univ of North Carolina Chapel Hill · NIH-11053626 · Data updated 2026-11-12

This study is testing a special exercise program for people with knee osteoarthritis to help them stay active and feel better, starting with home exercises and support, and offering extra help if they need it.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startApril 1, 2024
Project endSeptember 30, 2025
Funding year2025
Award (this year)$122,648
NIH project number5R34AR083077-02
Project IDNIH-11053626 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults aged 21 and older who are experiencing knee osteoarthritis and are currently inactive.

Less likely to help

Patients with knee osteoarthritis who are already actively engaged in regular exercise or physical therapy may not benefit from this research.

What this research studies

This research investigates a structured exercise program designed specifically for individuals with knee osteoarthritis (OA). The program starts with home-based exercises and includes behavioral support tools to encourage participation. If patients do not see improvement after three months, they receive telephone coaching, and if necessary, they can progress to physical therapy. This stepwise approach aims to integrate exercise into clinical care more effectively and improve patient outcomes.

Why it matters

Potential benefit: If successful, this research could lead to improved pain management and functional ability for patients with knee osteoarthritis.

How similar studies have gone: Previous research has shown that structured exercise programs can significantly improve outcomes for patients with knee osteoarthritis, indicating that this approach has potential for success.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Allen, Kelli D. — Univ of North Carolina Chapel Hill
  • Study coordinator: Allen, Kelli D.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.