A portable tool for detecting ribonucleases in RNA production.
Official title: Convenient rapid and portable tool for the detection of ribonucleases
Funded at Attogene · NIH-10760552 · Data updated 2026-11-12
This study is working on a quick and easy tool to help make sure that RNA, which is important for certain treatments and vaccines, stays safe and intact during production, so it can work better for patients.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Attogene NIH-funded |
| Lab location | 1 site (Austin, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $229,975 |
| NIH project number | 1R43GM151920-01 |
| Project ID | NIH-10760552 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals requiring RNA-based therapies, such as those with genetic disorders or certain cancers.
✕Less likely to help
Patients who are not candidates for RNA-based therapies or those with conditions unrelated to RNA manipulation may not receive benefits from this research.
What this research studies
This research focuses on developing a convenient and rapid tool to detect ribonucleases, which are enzymes that can degrade RNA. By ensuring RNA is produced in a controlled, RNAse-free environment, the project aims to enhance the quality and safety of RNA-based therapeutics and diagnostics. The approach involves creating a prototype that can be used in real-world applications, particularly in large-scale manufacturing settings. This tool will help maintain the integrity of RNA during production, which is crucial for the effectiveness of RNA therapies and vaccines.
Why it matters
Potential benefit: If successful, this research could significantly improve the reliability and safety of RNA-based treatments and diagnostics for patients.
How similar studies have gone: Other research has shown success in developing RNA-based therapies, indicating that advancements in RNA detection and quality control could lead to significant improvements in treatment efficacy.
Where this research is happening
-
Attogene
Austin, United States Active
Researchers
- Principal investigator: Ford, Lance P — Attogene
- Study coordinator: Ford, Lance P
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.