A portable system to detect and treat opioid overdoses
An automated portable system for detecting and treating opioid induced respiratory depression
This study is working on a handy device that can quickly spot and treat breathing problems caused by opioid overdoses, using wearable sensors and patches that deliver medicine right through the skin, to help save lives when help isn't nearby.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Trustees of Indiana University NIH-funded |
| Lab location | 1 site (Bloomington, United States) |
| Project ID | NIH-10796887 on NIH RePORTER |
What this research studies
This research aims to create an automated, portable system that can detect and treat opioid-induced respiratory depression in real time. It focuses on developing wearable sensors that monitor vital physiological parameters and therapeutic patches that deliver naloxone transdermally. The goal is to provide immediate intervention during an opioid overdose, especially in situations where traditional methods may be ineffective or unavailable. By enhancing detection and treatment capabilities, this project seeks to improve patient outcomes in critical situations.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who are prescribed opioids for pain management and may be at risk of overdose.
Not a fit: Patients who do not use opioids or those who are not at risk of respiratory depression from opioid use may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the number of deaths from opioid overdoses by enabling timely and effective treatment.
How similar studies have performed: Other research has shown promise in developing wearable technology for health monitoring, indicating potential success for this novel approach.
Where this research is happening
Bloomington, United States
- Trustees of Indiana University — Bloomington, United States (Active)
Researchers
- Principal investigator: Mackie, Kenneth — Trustees of Indiana University
- Study coordinator: Mackie, Kenneth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.