A portable and easy-to-use device for administering Naloxone to reverse opioid overdoses

A Rugged, Reliable, Portable, Safe, and Simple Naloxone HCl Auto-Injector forLife-Saving Treatment of Opioid Overdose

NIH-funded research Pirouette Medical · NIH-10764158

This study is working on a simple and easy-to-use auto-injector for Naloxone, a lifesaving medicine that can help people who are having an opioid overdose, so that anyone nearby can quickly help in an emergency.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionPirouette Medical NIH-funded
Lab location1 site (Portsmouth, UNITED STATES)
Project IDNIH-10764158 on NIH RePORTER

What this research studies

This research focuses on developing a user-friendly auto-injector for Naloxone, a medication that can quickly reverse opioid overdoses. The device is designed for use by untrained bystanders in emergency situations, ensuring that it is safe, reliable, and effective. By simplifying the administration process, the goal is to increase the likelihood of timely intervention during an overdose, potentially saving lives. The project builds on previous successful designs to create a robust and portable solution for opioid overdose emergencies.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals at risk of opioid overdose, their family members, and bystanders who may witness an overdose.

Not a fit: Patients who are not at risk of opioid overdose or do not have access to the auto-injector may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce opioid overdose fatalities by making Naloxone more accessible and easier to administer in critical situations.

How similar studies have performed: Previous research has shown that auto-injectors for emergency medications, like epinephrine, have been successful, indicating a promising potential for this approach with Naloxone.

Where this research is happening

Portsmouth, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.