A platform to enhance ultrasound treatment for blood clots
Official title: ICorps- A Numerical Platform for Microbubble Enhanced Sonothrombolysis
Funded at Dynaflow, INC. · NIH-11237880 · Data updated 2026-11-12
This study is working on a new tool to help doctors find the best ways to use special sound waves and tiny bubbles to treat blood clots, making sure the treatment is just right for each patient.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dynaflow, INC. NIH-funded |
| Lab location | 1 site (Jessup, United States) |
| Project start | September 17, 2024 |
| Project end | September 16, 2025 |
| Funding year | 2025 |
| Award (this year) | $55,000 |
| NIH project number | 3R43HL172528-01S1 |
| Project ID | NIH-11237880 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients suffering from thrombosis or related conditions that require thrombolysis treatment.
✕Less likely to help
Patients with conditions that do not involve blood clotting or those who are not candidates for thrombolysis may not benefit from this research.
What this research studies
This research aims to develop a numerical platform that will assist in the planning and discovery of therapies using microbubble-augmented focused ultrasound (MBaFUS) for treating blood clots. By improving the understanding of how microbubbles interact with blood clots and surrounding tissues, the platform seeks to optimize treatment parameters tailored to individual patients. The approach combines advanced computational modeling with clinical applications to facilitate the transition of this innovative therapy from the lab to real-world medical settings.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective non-invasive treatments for blood clots, reducing the risk of complications associated with traditional methods.
How similar studies have gone: Previous research has shown promising results with microbubble-enhanced therapies, indicating potential for success in this novel approach.
Where this research is happening
-
Dynaflow, INC.
Jessup, United States Active
Researchers
- Principal investigator: Ma, Jingsen — Dynaflow, INC.
- Study coordinator: Ma, Jingsen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.