A platform to enhance ultrasound treatment for blood clots

ICorps- A Numerical Platform for Microbubble Enhanced Sonothrombolysis

['FUNDING_SBIR_1'] · DYNAFLOW, INC. · NIH-11237880

This study is working on a new tool to help doctors find the best ways to use special sound waves and tiny bubbles to treat blood clots, making sure the treatment is just right for each patient.

Quick facts

Phase['FUNDING_SBIR_1']
Study typeNih_funding
SexAll
SponsorDYNAFLOW, INC. (nih funded)
Locations1 site (JESSUP, UNITED STATES)
Trial IDNIH-11237880 on ClinicalTrials.gov

What this research studies

This research aims to develop a numerical platform that will assist in the planning and discovery of therapies using microbubble-augmented focused ultrasound (MBaFUS) for treating blood clots. By improving the understanding of how microbubbles interact with blood clots and surrounding tissues, the platform seeks to optimize treatment parameters tailored to individual patients. The approach combines advanced computational modeling with clinical applications to facilitate the transition of this innovative therapy from the lab to real-world medical settings.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients suffering from thrombosis or related conditions that require thrombolysis treatment.

Not a fit: Patients with conditions that do not involve blood clotting or those who are not candidates for thrombolysis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to safer and more effective non-invasive treatments for blood clots, reducing the risk of complications associated with traditional methods.

How similar studies have performed: Previous research has shown promising results with microbubble-enhanced therapies, indicating potential for success in this novel approach.

Where this research is happening

JESSUP, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.