A platform for mapping gene activity in tissues
Official title: A democratized platform for mapping the spatial epigenome in tissue
Funded at Atlasxomics INC. · NIH-10931681 · Data updated 2026-11-12
This study is working on new tools to help scientists see how genes are arranged and active in tissues, which could improve our understanding of diseases like cancer and heart problems, ultimately leading to better treatments for patients.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Atlasxomics INC. NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | September 19, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $454,975 |
| NIH project number | 5R44CA287890-02 |
| Project ID | NIH-10931681 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals with cancer or cardiovascular diseases where epigenetic factors play a role.
✕Less likely to help
Patients with conditions unrelated to epigenetic dysregulation may not receive direct benefits from this research.
What this research studies
This research focuses on developing advanced tools to analyze the spatial arrangement of genes and their activity within tissues. By utilizing a technique called spatial ATAC-seq, the project aims to provide a deeper understanding of how epigenetic changes contribute to diseases like cancer and cardiovascular conditions. The approach involves creating a suite of hardware and software that allows researchers to visualize and interpret gene expression in a more detailed manner, which could lead to better therapeutic strategies. Patients may benefit indirectly as these tools enhance the understanding of disease mechanisms and treatment responses.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic and therapeutic strategies for diseases influenced by epigenetic changes.
How similar studies have gone: Other research has shown success with similar spatial biology approaches, indicating a promising avenue for understanding complex diseases.
Where this research is happening
-
Atlasxomics INC.
New Haven, United States Active
Researchers
- Principal investigator: Sabina, Jeffrey — Atlasxomics INC.
- Study coordinator: Sabina, Jeffrey
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.