NIH-funded research Sbir 2 grant

A platform for advanced brain activity monitoring

Official title: A commercialized platform for diversified large-scale chronic electrophysiology

Funded at Spikegadgets, LLC · NIH-10921067 · Data updated 2026-11-12

This study is working on a new technology that will help scientists better understand brain activity by creating a special device with many tiny sensors, making it easier to study how the brain works in different animals and situations.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionSpikegadgets, LLC
NIH-funded
Lab location1 site (San Francisco, UNITED STATES)
Project startJuly 16, 2024
Project endJune 30, 2026
Funding year2024
Award (this year)$1,016,232
NIH project number1R44MH136865-01
Project IDNIH-10921067 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation or benefit from this research would include individuals with neurological disorders or conditions that affect brain function.

Less likely to help

Patients with acute neurological injuries or those not involved in research settings may not receive direct benefits from this research.

What this research studies

This research focuses on developing a commercial platform that enhances the capabilities of multi-electrode arrays (MEAs) used in chronic electrophysiology. By creating a compact 512-channel integrated circuit known as the EChip, the project aims to allow manufacturers to produce MEAs with significantly more electrodes, improving the study of brain activity and behavior. The project will also develop versatile electronics and software to facilitate the use of these advanced MEAs in various experimental settings and species.

Why it matters

Potential benefit: If successful, this research could lead to more effective tools for studying brain function and behavior, potentially improving treatments for neurological conditions.

How similar studies have gone: Other research has shown success in enhancing electrophysiological tools, indicating that this approach has the potential for significant advancements.

Where this research is happening

  • Spikegadgets, LLC
    San Francisco, United States
    Active

Researchers

  • Principal investigator: Karlsson, Mattias Peter — Spikegadgets, LLC
  • Study coordinator: Karlsson, Mattias Peter

Related research

Other NIH-funded projects on the same topics.

  • Developing advanced technology for studying brain activity

    This study is working on a new tool that can safely and effectively track the activity of many brain cells in rodents, which could help us learn more about how the brain works and improve technology for studying brain health.

    NIH research Spikegadgets, LLC · San Francisco, UNITED STATES · NIH-10897943

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.