A Personalized Methadone Dosing System

Methadone Dosing System (MDS)

['FUNDING_OTHER'] · CARI HEALTH, INC. · NIH-11324767

This project is creating a new way to figure out the right methadone dose for each person to help them overcome opioid addiction more effectively.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorCARI HEALTH, INC. (nih funded)
Locations1 site (SAN DIEGO, UNITED STATES)
Trial IDNIH-11324767 on ClinicalTrials.gov

What this research studies

Many people trying to stop opioid use face tough withdrawal symptoms, which can make it hard to continue treatment. Methadone is a helpful medicine, but how well it works can vary a lot from person to person due to differences in their body's metabolism. This project aims to develop a new, science-based approach to methadone dosing that considers your unique metabolism. The goal is to find the perfect dose for you, reducing side effects and preventing withdrawal symptoms, to make your journey to recovery smoother.

Who could benefit from this research

Good fit: This approach is designed for individuals seeking treatment for opioid use disorder who are prescribed methadone.

Not a fit: Patients not undergoing methadone maintenance treatment for opioid use disorder would not directly benefit from this specific dosing system.

Why it matters

Potential benefit: If successful, this system could lead to more effective and personalized methadone treatment, helping more patients overcome opioid addiction with fewer withdrawal symptoms and side effects.

How similar studies have performed: Current methadone dosing often follows general guidelines, so this project introduces a novel, personalized approach based on individual metabolism.

Where this research is happening

SAN DIEGO, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.