A patch to treat narrowing of the airway in children
Nanofiber Patch with Gradient Presentation of Biomolecules for Treatment of Pediatric Tracheal Stenosis
This study is testing a special patch that could help kids with tracheal stenosis, a condition where their airway gets too narrow, by making it easier for them to breathe and heal without needing complicated surgeries.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Colorado State University NIH-funded |
| Lab location | 1 site (Fort Collins, United States) |
| Project ID | NIH-10989143 on NIH RePORTER |
What this research studies
This research focuses on developing a synthetic patch designed to treat pediatric tracheal stenosis, a serious condition where the airway narrows. The patch aims to mimic the natural healing environment and is engineered to be mechanically strong, suturable, resorbable, air-tight, and readily available. By using advanced biomaterials and a gradient presentation of biological factors, the goal is to maintain airway patency and promote healing without the need for complex surgical procedures. This innovative approach addresses a significant unmet need in pediatric otolaryngology.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-21 who are diagnosed with tracheal stenosis.
Not a fit: Patients with tracheal stenosis who are not eligible for surgical intervention or those with other complicating medical conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a safer and more effective treatment option for children suffering from tracheal stenosis.
How similar studies have performed: While similar approaches in tissue engineering have been explored, this specific application of a synthetic patch for tracheal stenosis is novel and has not been tested in this manner before.
Where this research is happening
Fort Collins, United States
- Colorado State University — Fort Collins, United States (Active)
Researchers
- Principal investigator: Townsend, Jakob — Colorado State University
- Study coordinator: Townsend, Jakob
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.