A non-surgical solution for gallstone disease
Official title: Koli: A non-surgical solution for gallstone disease
Funded at Koli, INC. · NIH-10912509 · Data updated 2026-11-12
This study is looking at a new, non-surgical way to help people with gallstone problems who can't have surgery, aiming to make them feel better and avoid complications.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Koli, INC. NIH-funded |
| Lab location | 1 site (Palo Alto, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $766,033 |
| NIH project number | 5R44DK135204-02 |
| Project ID | NIH-10912509 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with symptomatic gallstone disease who are at high risk for surgery due to comorbidities or other health issues.
✕Less likely to help
Patients who are healthy enough to undergo surgical treatment for gallstone disease may not benefit from this research.
What this research studies
This research investigates a new non-surgical approach to treat symptomatic gallstone disease, which affects millions of people in the U.S. The focus is on developing a treatment that can be administered to patients who are unable to undergo surgery due to various health complications. By exploring innovative methods to manage gallstones, the research aims to reduce the risks associated with surgical interventions and improve patient outcomes. The study will involve evaluating the effectiveness of this new treatment in alleviating symptoms and preventing complications related to gallstones.
Why it matters
Potential benefit: If successful, this research could provide a safer alternative for patients suffering from gallstone disease who cannot undergo surgery.
How similar studies have gone: While surgical treatments for gallstone disease are well-established, this non-surgical approach is novel and has not been extensively tested in prior research.
Where this research is happening
-
Koli, INC.
Palo Alto, United States Active
Researchers
- Principal investigator: Cheng, Christopher — Koli, INC.
- Study coordinator: Cheng, Christopher
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.