A non-surgical solution for gallstone disease

Koli: A non-surgical solution for gallstone disease

NIH-funded research Koli, INC. · NIH-10912509

This study is looking at a new, non-surgical way to help people with gallstone problems who can't have surgery, aiming to make them feel better and avoid complications.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionKoli, INC. NIH-funded
Lab location1 site (Palo Alto, United States)
Project IDNIH-10912509 on NIH RePORTER

What this research studies

This research investigates a new non-surgical approach to treat symptomatic gallstone disease, which affects millions of people in the U.S. The focus is on developing a treatment that can be administered to patients who are unable to undergo surgery due to various health complications. By exploring innovative methods to manage gallstones, the research aims to reduce the risks associated with surgical interventions and improve patient outcomes. The study will involve evaluating the effectiveness of this new treatment in alleviating symptoms and preventing complications related to gallstones.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with symptomatic gallstone disease who are at high risk for surgery due to comorbidities or other health issues.

Not a fit: Patients who are healthy enough to undergo surgical treatment for gallstone disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a safer alternative for patients suffering from gallstone disease who cannot undergo surgery.

How similar studies have performed: While surgical treatments for gallstone disease are well-established, this non-surgical approach is novel and has not been extensively tested in prior research.

Where this research is happening

Palo Alto, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.