A new way to identify factors that influence biological aging using advanced DNA analysis.
A novel method to identify regulators of biological aging based on high-throughput sequencing of epigenetic clocks.
This study is looking for a new, affordable way to check how our DNA changes as we age, using a special method that can look at many samples at once, to help us understand aging better and find new ways to improve health as we get older.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard University NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project ID | NIH-10913641 on NIH RePORTER |
What this research studies
This research focuses on developing a cost-effective method to analyze DNA methylation patterns, which are indicators of biological aging. By using a novel technique called TIME-Seq, the researchers aim to measure epigenetic clocks across multiple samples simultaneously, making it easier to study aging and its potential interventions. The goal is to uncover the biological mechanisms behind aging and identify new genes associated with it, which could lead to better understanding and treatment options for age-related conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals interested in aging-related studies or those undergoing interventions aimed at slowing aging.
Not a fit: Patients who are not interested in aging research or those with no age-related health concerns may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding aging and developing interventions that may slow down the aging process.
How similar studies have performed: Other research has shown promise in using DNA methylation as a biomarker for aging, but this specific approach is novel and has not been widely tested.
Where this research is happening
Cambridge, United States
- Harvard University — Cambridge, United States (Active)
Researchers
- Principal investigator: Griffin, Patrick — Harvard University
- Study coordinator: Griffin, Patrick
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.