NIH-funded research R01 grant

A new way to help cancer patients who smoke quit using e-cigarettes.

Official title: A Novel Harm Reduction Approach for Oncology Outpatients who Smoke and Refuse Traditional Tobacco Treatment

Funded at Medical University of South Carolina · NIH-11057820 · Data updated 2026-11-12

This study is looking at whether helping cancer patients who smoke switch to e-cigarettes is more effective than regular smoking help programs, and it’s for those who want to quit but haven’t found success with traditional methods.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMedical University of South Carolina
NIH-funded
Lab location1 site (Charleston, United States)
Project startDecember 1, 2024
Project endNovember 30, 2029
Funding year2025
Award (this year)$619,175
NIH project number1R01CA293735-01A1
Project IDNIH-11057820 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are oncology outpatients who currently smoke and have refused traditional tobacco cessation treatments.

Less likely to help

Patients who do not smoke or those who are already engaged in successful tobacco cessation programs may not benefit from this research.

What this research studies

This research investigates a novel approach to assist oncology outpatients who smoke and refuse traditional tobacco treatments. It aims to compare the effectiveness of switching from cigarettes to e-cigarettes against standard care methods. The study will involve 208 participants who will be randomly assigned to either an e-cigarette switching program or a control group receiving standard tobacco treatment resources. By understanding the barriers and facilitators to implementing this approach, the research seeks to improve smoking cessation among cancer patients.

Why it matters

Potential benefit: If successful, this research could provide a more appealing and effective method for cancer patients to quit smoking, potentially reducing their cancer risk and improving treatment outcomes.

How similar studies have gone: Other research has shown promise in using e-cigarettes as a harm reduction strategy for smokers, indicating potential success for this novel approach.

Where this research is happening

  • Medical University of South Carolina
    Charleston, United States
    Active

Researchers

  • Principal investigator: Rojewski, Alana — Medical University of South Carolina
  • Study coordinator: Rojewski, Alana

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.