A New Way to Find Sepsis Early
Solid-state nanopore detection of protein biomarkers for early sepsisdiagnosis
['FUNDING_R01'] · UNIVERSITY OF MISSOURI-COLUMBIA · NIH-11124875
This project is creating a new, fast test to help doctors find sepsis sooner by looking for many signs in a patient's blood.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MISSOURI-COLUMBIA (nih funded) |
| Locations | 1 site (COLUMBIA, UNITED STATES) |
| Trial ID | NIH-11124875 on ClinicalTrials.gov |
What this research studies
Sepsis is a very serious condition that can be hard to diagnose quickly because its early signs are often vague. Delays in finding sepsis can lead to worse outcomes and even death. This project aims to build a special device that can detect several important markers of sepsis at once from a small sample. By identifying these markers together, doctors could get a more complete picture, leading to earlier and more accurate diagnosis. This could help patients get the right treatment much faster.
Who could benefit from this research
Good fit: Patients at risk for or showing early, non-specific symptoms of sepsis would be the primary beneficiaries of this diagnostic tool once it is developed and available.
Not a fit: Patients who do not have or are not at risk for sepsis would not directly benefit from this specific diagnostic development.
Why it matters
Potential benefit: If successful, this new technology could provide a much faster and more accurate way to diagnose sepsis, potentially saving lives and improving patient outcomes.
How similar studies have performed: While current clinical methods often look for one specific biomarker, this approach combines several advanced techniques to detect multiple biomarkers simultaneously, representing a novel strategy.
Where this research is happening
COLUMBIA, UNITED STATES
- UNIVERSITY OF MISSOURI-COLUMBIA — COLUMBIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GUAN, XIYUN — UNIVERSITY OF MISSOURI-COLUMBIA
- Study coordinator: GUAN, XIYUN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.