A new way to find active tuberculosis cases in adolescents
Official title: A new method for active tuberculosis case finding
Funded at Muhimbili University/ Allied Hlth Scis · NIH-11055303 · Data updated 2026-11-12
This study is looking to help find more cases of active tuberculosis (TB) in teenagers by testing the people they live with, so we can catch more infections early and keep everyone healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Muhimbili University/ Allied Hlth Scis NIH-funded |
| Lab location | 1 site (Dar Es Salaam, Tanzania U Rep) |
| Project start | April 6, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $133,231 |
| NIH project number | 5R01AI176581-03 |
| Project ID | NIH-11055303 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adolescents aged 0-21 years who are household contacts of individuals recently diagnosed with tuberculosis.
✕Less likely to help
Patients who are not adolescents or those who do not have a household contact with recently diagnosed tuberculosis may not benefit from this research.
What this research studies
This research focuses on improving the detection of active tuberculosis (TB) in adolescents by testing their household contacts. The current method only identifies a small percentage of undiagnosed cases, but this new approach aims to significantly increase that number by targeting recently diagnosed adolescents. By conducting regular testing over a five-year period, the study will track TB infections and identify potential source cases among close contacts. This innovative method is based on previous successful testing in Tanzanian schoolchildren.
Why it matters
Potential benefit: If successful, this research could lead to a more effective way of identifying and treating tuberculosis in adolescents, ultimately reducing the spread of the disease.
How similar studies have gone: Previous studies have shown success in using serial testing methods for tuberculosis detection, indicating that this approach has potential for effective outcomes.
Where this research is happening
-
Muhimbili University/ Allied Hlth Scis
Dar Es Salaam, Tanzania U Rep Active
Researchers
- Principal investigator: Amour, Maryam — Muhimbili University/ Allied Hlth Scis
- Study coordinator: Amour, Maryam
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.