A new way to diagnose heart failure with preserved ejection fraction using advanced imaging techniques.

A Multiscale Computational Model of the Heart for Patient-specific Diagnosis of HFpEF

NIH-funded research Emory University · NIH-10998663

This study is working on a new way to help doctors better diagnose heart failure with preserved ejection fraction (HFpEF) by using MRI scans to create a personalized model of your heart, which can show how stiff your heart muscle is and help predict how the condition might progress.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionEmory University NIH-funded
Lab location1 site (Atlanta, United States)
Project IDNIH-10998663 on NIH RePORTER

What this research studies

This research focuses on improving the diagnosis of heart failure with preserved ejection fraction (HFpEF), a condition where patients exhibit heart failure symptoms despite having normal heart function. The approach involves creating a patient-specific computational model that uses non-invasive MRI data to estimate the stiffness of the heart muscle, which is crucial for understanding the condition. By analyzing the heart's biomechanical properties, the research aims to provide a more accurate diagnosis and predict disease progression, potentially leading to better patient outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with heart failure who have preserved ejection fraction and exhibit symptoms of the condition.

Not a fit: Patients with heart failure who do not have preserved ejection fraction or those with other unrelated cardiac conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and timely diagnoses of HFpEF, allowing for improved management and treatment of patients.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for cardiac conditions, suggesting that this novel approach could be effective.

Where this research is happening

Atlanta, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.