A new way to diagnose heart failure with preserved ejection fraction using advanced imaging techniques.
Official title: A Multiscale Computational Model of the Heart for Patient-specific Diagnosis of HFpEF
Funded at Emory University · NIH-10998663 · Data updated 2026-11-12
This study is working on a new way to help doctors better diagnose heart failure with preserved ejection fraction (HFpEF) by using MRI scans to create a personalized model of your heart, which can show how stiff your heart muscle is and help predict how the condition might progress.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | September 30, 2024 |
| Project end | September 29, 2027 |
| Funding year | 2024 |
| Award (this year) | $48,974 |
| NIH project number | 1F31HL172683-01A1 |
| Project ID | NIH-10998663 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with heart failure who have preserved ejection fraction and exhibit symptoms of the condition.
✕Less likely to help
Patients with heart failure who do not have preserved ejection fraction or those with other unrelated cardiac conditions may not benefit from this research.
What this research studies
This research focuses on improving the diagnosis of heart failure with preserved ejection fraction (HFpEF), a condition where patients exhibit heart failure symptoms despite having normal heart function. The approach involves creating a patient-specific computational model that uses non-invasive MRI data to estimate the stiffness of the heart muscle, which is crucial for understanding the condition. By analyzing the heart's biomechanical properties, the research aims to provide a more accurate diagnosis and predict disease progression, potentially leading to better patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and timely diagnoses of HFpEF, allowing for improved management and treatment of patients.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for cardiac conditions, suggesting that this novel approach could be effective.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Hussein, Tawfik — Emory University
- Study coordinator: Hussein, Tawfik
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.