A new way to control liver damage in fatty liver disease
A novel pathway controls liver injury in NASH
['FUNDING_R01'] · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · NIH-11084431
This study is looking into how nonalcoholic steatohepatitis (NASH) damages the liver and aims to find new ways to help treat it, which could be really helpful for people living with this condition.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TEXAS HLTH SCIENCE CENTER (nih funded) |
| Locations | 1 site (SAN ANTONIO, UNITED STATES) |
| Trial ID | NIH-11084431 on ClinicalTrials.gov |
What this research studies
This research investigates the underlying mechanisms of liver injury caused by nonalcoholic steatohepatitis (NASH), a serious condition that can lead to cirrhosis and liver cancer. The study focuses on understanding how liver cell death occurs and how it can be controlled, which is crucial for developing new treatments. By examining the molecular pathways involved in this process, researchers aim to identify potential therapeutic targets that could reverse the effects of NASH. Patients with NASH may benefit from this research as it seeks to uncover new strategies for treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with nonalcoholic steatohepatitis (NASH) who are experiencing liver injury.
Not a fit: Patients with liver conditions unrelated to NASH or those who do not have liver injury may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies for patients suffering from nonalcoholic steatohepatitis, potentially reversing liver damage.
How similar studies have performed: Previous research has shown promise in understanding liver injury mechanisms in similar conditions, indicating potential for success in this novel approach.
Where this research is happening
SAN ANTONIO, UNITED STATES
- UNIVERSITY OF TEXAS HLTH SCIENCE CENTER — SAN ANTONIO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZHAO, PENG — UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
- Study coordinator: ZHAO, PENG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.