A new vaccine approach to prevent recurrent genital herpes
A Novel Prime/Pull Therapeutic Vaccine Strategy to Prevent Recurrent Genital Herpes
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA-IRVINE · NIH-10747850
This study is working on a new vaccine to help prevent repeat outbreaks of genital herpes for people who have the virus, focusing on how the immune system can be trained to fight it better.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA-IRVINE (nih funded) |
| Locations | 1 site (IRVINE, UNITED STATES) |
| Trial ID | NIH-10747850 on ClinicalTrials.gov |
What this research studies
This research aims to develop a therapeutic vaccine to prevent recurrent genital herpes caused by the herpes simplex virus type 2 (HSV-2). The approach involves identifying specific viral proteins that can stimulate the immune system to produce protective T cells. By studying the immune responses of asymptomatic women and animal models, the researchers hope to create a vaccine that can effectively reduce the frequency of outbreaks in infected individuals. The project is ongoing and aims to provide a viable vaccine option for millions affected by this condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who are infected with HSV-2 and experience recurrent genital herpes.
Not a fit: Patients who are not infected with HSV-2 or those who do not experience recurrent outbreaks may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a vaccine that significantly reduces the occurrence of recurrent genital herpes outbreaks.
How similar studies have performed: Previous research has shown promise in developing vaccines targeting similar viral infections, but this specific approach is novel and untested.
Where this research is happening
IRVINE, UNITED STATES
- UNIVERSITY OF CALIFORNIA-IRVINE — IRVINE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BENMOHAMED, LBACHIR — UNIVERSITY OF CALIFORNIA-IRVINE
- Study coordinator: BENMOHAMED, LBACHIR
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.